Antelope Valley

City of Hope provides Antelope Valley, Lancaster and its surrounding communities with incomparable cancer care and innovative treatments close to home.

The convenient location, just off Highway 14, puts our patients within easy reach of additional medical, laboratory and diagnostic radiology services, such as ultrasound, mammograms, MRI (magnetic resonance imaging) and CT (computed tomography) scans.

34.6855732, -118.1584387

44151 15th Street West
Lancaster, CA 93534

(877) 828-3627

Monday through Friday: 8 a.m. to 5 p.m.

Closed on major federal holidays

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Our Physicians
Insurance Information

APEx American Society of Radiation Oncology (ASTRO) badge

City of Hope cares for patients from prevention through survivorship by pairing our expertise in numerous cancers and conditions with world-class technologies and services.

The radiation oncology program at City of Hope | Antelope Valley has earned APEx accreditation, the highest level of certification offered by the American Society for Radiation Oncology (ASTRO).

Medical Oncology

Our multidisciplinary team of physicians, researchers, nurse practitioners and health professionals work together on a wide variety of solid tumors from diagnosis to treatment. We offer our patients the latest advances in chemotherapy, hormonal therapy, biologic therapy, targeted therapy and other innovative therapies.

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Hematology and Hematology - Oncology

Our nationally recognized experts treat blood cancers, as well as disorders relating to blood and tissues. With ongoing research and groundbreaking clinical trials, City of Hope offers treatment plans with the most innovative therapies available anywhere.

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Hematology and Hematology - Oncology - Pediatric

Our dedicated team consists of world-class professionals specially trained in the treatment of pediatric, adolescent and young adult cancer and blood diseases. Specializing in the diagnosis and treatment of both benign and malignant tumors, as well as a variety of blood disorders, our board-certified pediatric oncologists and hematologists work together with others to develop a targeted and effective treatment plans.

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Surgery - Surgical Oncology

Our surgical oncologists are highly skilled and versatile, each with expertise in the latest techniques for the surgical management and treatment of a wide variety of cancers.

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Surgery - General

Our surgeons are highly skilled with expertise in a wide range of conditions and procedures, including appendectomy, gall bladder removal, hemorrhoids and hernias.

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Urology and Urologic Oncology

City of Hope’s highly skilled urologists treat bladder, prostate and kidney cancers as well as a wide spectrum of diseases of the urinary tract and the male reproductive system.

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Radiation Oncology

City of Hope’s radiation oncology program is one of the largest and most experienced in Southern California. We offer a comprehensive set of specialized services and advanced technologies, planned and provided by our uniquely trained staff, for a broad range of cancer diagnoses.

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Chemotherapy/Infusion Therapy

Our medical oncologists will work with patients to develop a personalized treatment plan using chemotherapy drugs, as well as other treatment options. We offer an open, comfortable and comforting environment with a compassionate and attentive staff to administer and monitor your treatment.

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Clinical Trials

Patients have the opportunity to participate in clinical trials involving the newest drugs and treatments before they are widely available.

Physician Dispensing

We offer on-site dispensing of most oral oncolytics and other related supportive care medication. Ask our office manager for details.

City of Hope is dedicated to creating a positive and healing environment in our spacious chemotherapy and infusion area. Features such as private TV sets with cone speakers, large and relaxing chairs, warm blankets, a break room stocked with healthy snacks and free guest Wi-Fi all contribute to making our patients’ time here for treatment as comfortable as possible.

Express Check-In Kiosk

After your first visit, you can access our self-check-in kiosk and be able to:

Check in for your appointments and print your itinerary
Make a payment online with Visa, MasterCard or Discover (debit/credit)
Sign up for the MyCityofHope patient portal

Please note, the kiosk service is not available if you are visiting for the first time, your name and insurance has changed since your last visit, or if you will be making your co-payment with cash, check or debit card.

City of Hope is home to many of the nation's leading cancer doctors. With clinical specialities that span all of medicine, multi-lingual and many locations to fit your needs. Find a physician that fits you today.

Is My Insurance Accepted?

View a list of insurance companies that City of Hope currently contracts with for its locations and physicians. Even if your plan is included, check with your insurance company to make sure you are covered. Your insurance company/medical group will tell you if you need any authorizations.

If you wish to receive treatment at City of Hope, but we're not currently contracted with your insurance plan, contact your insurance company and ask about obtaining authorization to receive treatment here.

View our pricing and billing

Provider based billing

No Surprise Billing

When you're treated by an out-of-network provider at an in-network facility, you are protected from balance billing. In these cases, you shouldn't be charged more than your plan's copayments, coinsurance and/or deductible. Learn about your rights and protections against surprise medical bills.

Explore City of Hope | Antelope Valley

The light and bright 25,000-square-foot facility offers multiple exam and treatment rooms for patient comfort and convenience, expanding access to City of Hope’s world-class level of care.

Our Physicians

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Clarke Anderson, M.D.

Pediatric Hematologist-Oncologist

Duarte - Main Campus; Antelope Valley; South Pasadena; Upland

Clarke Anderson, M.D., is City of Hope's go-to professional for handling difficult and often heart-rending cases of cancer in small children, especially neuroblastomas, or tumors of the central nervous system.

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Hannah Asghari, M.D.

Medical Oncologist and Hematologist

Antelope Valley

Hannah Asghari, M.D., is a medical oncologist and hematologist in the Department of Medical Oncology & Therapeutics Research.

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Mary Cianfrocca, D.O., M.B.A.

Medical Oncologist

Duarte - Main Campus; Antelope Valley

Mary Cianfrocca, D.O., M.B.A., is a medical oncologist at City of Hope's cancer research hospital.

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Maria C.B. de Leon, M.D.

Gynecologic Oncologist

Antelope Valley; Mission Hills; Santa Clarita

Maria de Leon, M.D., is an assistant clinical professor in City of Hope's Division of Gynecologic Oncology, specializing in diagnosis and treatment of cervical, endometrial/uterine and ovarian cancers.

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Boryana Eastman, M.D., Ph.D.

Radiation Oncologist

Antelope Valley

Boryana Eastman, M.D., Ph.D., is an assistant professor in the Department of Radiation Oncology at City of Hope.

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George Hajjar, M.D.

Medical Oncologist and Hematologist

Santa Clarita; Antelope Valley

George Hajjar, M.D., is a medical oncologist and regional medical director for San Fernando Valley, Santa Clarita Valley and Ventura County.

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Trevor Lim, M.D.

Radiation Oncologist

Antelope Valley

Trevor Lim, M.D., chose his specialty in radiation oncology because it gives him the chance to eradicate cancer with pinpoint precision and minimal side effects for his patients. Helping people with cancer live longer, healthier lives in this way drives his work as a physician.

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Amartej Merla, M.D.

Medical Oncologist and Hematologist

Antelope Valley; Palmdale

Amartej Merla, M.D., is a medical oncologist and hematologist with expertise in hematological cancers as well as gastrointestinal, stomach, esophageal and colorectal cancers. He practices at City of Hope's Antelope Valley location.

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